Although Oracle's VirtualBox runs normally under the new October 2018 update of Windows 10, it refuses to open any Interactive machine.
When upgrading and installing the new Windows 2018 October 10 update, the functional system had warned us that the known software found in our computer scan, Oracle's VirtualBox, is not compatible with version 1809.
So we proceeded to remove it and after the update of Windows 10 we installed the latest version of VirtualBox, 5.2.18-124319 in 32bit environment. The application opened just fine, everything seemed perfect, but it refused to run any virtual machine, either old or a new one we just created.
Searching the company's forums and tickets we discovered that the problem was known to the company 4 weeks ago (!!!) by insiders users of Windows. The company's response then was that "we work but do not have the time"
Of course there is corresponding thread in the Oracle forum where the problem is reported and the user proposes to test the current beta version (5.2.19), but neither did it work.
So wait for those who work with the free but unnecessary for now, Oracle VirtualBox.
