Although Oracle's VirtualBox runs normally under the new October 2018 update of Windows 10, it refuses to open any Interactive machine.
At upgrade and installing the new October 2018 update of Windows 10, the operating system had warned us that the known software found in the scan of our computer, Oracle's VirtualBox, is not compatible with version 1809.
So we proceeded to remove it and after the update of Windows 10 we installed the latest version of VirtualBox, 5.2.18-124319 in 32bit environment. The application opened just fine, everything seemed perfect, but it refused to run any virtual machine, either old or a new one we just created.
Looking at the company's forums and bids, we found out that the problem was known to 4 a few weeks ago (!!!) by insider Windows users. The company's response then ήταν ότι "το δουλεύουμε αλλά δεν έχουμε τον χρόνο"
Of course there is corresponding thread in the Oracle forum where the problem is reported and user suggests essay of today's beta version (5.2.19), but that didn't work either.
So wait for those who work with the free but unnecessary for now, Oracle VirtualBox.